Health Care

Akumin Inc. (TSX-V: AKU) is a leading provider of free-standing, fixed-site outpatient diagnostic imaging services in the United States with a network of 71 owned and/or operated imaging centres located in Florida, Pennsylvania, Delaware, Texas, Illinois and Kansas. By combining its clinical expertise with the latest advances in technology and information systems, the company’s centres provide physicians with imaging capabilities to facilitate the diagnosis and treatment of diseases and disorders and may reduce unnecessary invasive procedures, minimizing the cost and amount of care for patients. PowerOne was an early shareholder and works closely with management. PowerOne has also acted as finder for a US$3.5 million non-brokered financing in August 2015 and a US$5.6 million non-brokered financing in May 2016. PowerOne acted as co-lead agent for a US$10.5 million financing in March of 2017 and co-lead agent for a US$34.8 million financing in August of 2017.

Ramm Pharma is a leader in the field of cannabinoid pharmacology and product formulation for cannabis-based pharmaceuticals and other cannabis-based products with a unique and diversified international production and sales platform. The company operates an established pharmaceutical and medical product business in Uruguay that has developed several medically registered and approved plant-derived cannabinoid pharmaceutical products that have been authorized for sale and/or compassionate use in several Latin American countries. Ramm also has a pipeline of new products, including registered cannabis-based nutrition and specialized veterinary products, in various stages of approval and development, which are produced at the company’s state-of-the-art, good-manufacturing-practice-certified cannabis formulation facility in Montevideo, Uruguay.

Aurora Spine Corporation, through its subsidiary, Aurora Spine, Inc., engages in the development and distribution of minimally invasive and interspinous fusion systems and devices in Canada. The company offers interspinous process lumbar fusion devices, such as the ZIP, ZIP ULTRA, ZIP LP, and ZIP-51 for patients suffering from degenerative disc diseases; Ti-Coated polyether ether ketone interbody cages, which provide spacing and stability between the vertebrae and bone grows to complete the fusion process; and sterile-packed titanium plasma spray coated spinal infusion implants for bone growth, as well as interbody products, such as EOS, VOX, Echo, Echo SD, and EchoXL for the lumbar section of the spine, and discovery for cervical procedures. It also provides SOLO, an anterior lumbar interbody fusion 3D printed stand-alone fusion device, which is an integrated plate and spacer system that helps to preserve the natural anatomic profile while providing spinal column support and stability; and pain management device, such as SiLo, a posterior fusion device for the sacroiliac joint. The company was incorporated in 2013 and is headquartered in Toronto, Canada.

Bedrocan BV has been producing and supplying pharmaceutical grade government regulated medical marijuana for 15 years. Bedrocan products are available under Medicinal Cannabis regulations in 7 countries globally. The PowerOne Group participated as a significant equity sponsor in the capitalization of the company as part of Bedrocan?s $4.4 million private placement in April 2014 for which PowerOne acted as Sole Agent. PowerOne also acted as Co-Agent for a $11.47 financing in July 2014; Financial Advisor in taking the Company public via an RTO with POCML 2 Inc., a PowerOne Sponsored CPC Vehicle on the TSX.V; and Co-Financial Advisor in its merger with Tweed Marijuana Inc. to become Canopy Growth Corp. (TSX-V: CGC), the largest public Medicinal Cannabis company in Canada. PowerOne was awarded the Private Capital Markets Association ?Deal of the Year Award? for its various engagements with Bedrocan in 2014.

Blueberries is a Latin American licensed producer of naturally grown premium quality cannabis with its primary operations ideally located in the BogotĀ  Savannah of central Colombia and operations currently being established in Argentina. Led by a specialized team with proprietary expertise in agriculture, genetics, extraction, medicine, pharmacology and marketing, Blueberries is fully licensed for the cultivation, production, domestic distribution, and international export of CBD and THC-based medical cannabis. Blueberries? combination of leading scientific expertise, agricultural advantages and distribution arrangements has positioned the Company to become a leading international supplier of naturally grown, processed, and standardized medicinal-grade cannabis oil extracts and related products.

Slang Worldwide is a Toronto-based company consolidating brands along the regulated supply chain in the global cannabis industry, building a world class portfolio of assets. The Company is focused on acquiring and developing market-proven regional brands, as well as creating new brands to meet the needs of cannabis consumers worldwide. PowerOne acted as co-agent in the company?s $16.7M financing in March 2018.

Merus Labs International Inc. is a specialty pharmaceutical company engaged in the acquisition and licensing of niche pharmaceutical products throughout North America. By capitalizing on its expertise of the North American pharmaceutical markets and access to capital, Merus is currently focused on building its portfolio of products. Merus strategically develops the sale and distribution of their product line by introducing a targeted re-launch marketing and promotional plan. PowerOne was instrumental in the creation of the company and has helped Merus raise over $100M in Debt and Equity since its inception.

Aleafia Health brings Canadians medical cannabis care through nationwide clinics, world-class cultivation and distribution facilities, and innovative research. Experiential knowledge of medical cannabis therapy, a rapidly evolving science, helps ensure physicians make recommendations that have been proven effective through historical data, helping to avoid treatments based on trial and error. The company?s staff of trained educators provide learning sessions for new patients, providing ongoing consultation ensuring patients are matched with the most appropriate treatment.

Alegro Health Corp. (TSX-V: AGO), a provider of medical, surgical and rehabilitation and disability management services.

Antisense Therapeutics is a biopharmaceutical drug discovery and development company whose mission is to create, develop and commercialize novel antisense therapeutics for a variety of drug candidates including Duchenne Muscular Dystrophy (DMD), Multiple Sclerosis (MS), and Acromegaly.

Canabo wholly owns and operates Cannabinoid Medical Clinics, or CMClinics, Canada’s largest physician led referral-only clinics for medical cannabis. Established in 2014, Canabo now has 22 clinics across Canada, with additional locations planned to open in 2018. Canabo operates referral-only medical clinics dedicated to evaluating the suitability of prescribing, and monitoring cannabinoid treatments for patients suffering from chronic pain and disabling illnesses. Clinics operated by Canabo are staffed by physicians and qualified health care practitioners specifically trained to assess patient suitability for cannabinoid treatment, recommend treatment regimes, and monitor treatment progress.

Canopy Growth advances the world?s perception of cannabis by focusing on research, product development and innovative production capabilities ? all presented through brands people trust.

ChondroGene Limited is focussed on the application of functional genomics to enable early diagnosis and personalized therapeutic intervention based on disease-specific biomarkers. The Company has developed a novel approach, the Sentinel Principle(TM), to detect and stage virtually any disease or medical condition from a simple blood sample. GeneNews is currently applying the Sentinel Principle in major areas with unmet clinical needs such as cancer, arthritis, cardiovascular disease and neurological disorders. GeneNews’ first product in development, ColonSentry(TM), is a blood-based test that can detect colon cancer and pre-cancerous polyps.

Diagnos is a leader in artificial intelligence and healthcare technical services including algorithm development, data analysis, and image processing ever since 2001. DIAGNOS Inc. of Canada provides software solutions. The Company develops and publishes a knowledge extraction platform that allows for the enhancement and intelligent analysis of digital retinal images. DIAGNOS serves healthcare industry worldwide.

Elite Imaging, Inc. provides medical imaging and radiology services. The Company offers magnetic resonance imaging (MRI), healthcare screening, breast implants, digital mammography, x-ray, nuclear medicine, and echocardiography services. Elite Imaging serves customers in the United States.

Lorus Therapeutics Inc. (TSX: LOR) (the “Company”), a clinical-stage company developing new therapeutics and molecular diagnostics that target the underlying mechanisms of cancer.

MediPharm Labs, a contract and development and manufacturing company, brings a pharmaceutical perspective to the cannabis industry; working to internationally recognized pharma-quality standards, our cannabis products that are PURE, TRUSTED and PRECISELY DOSABLE for patients and end consumers. MediPharm Labs Corp., together with its subsidiaries, produces and sells pharmaceutical-grade cannabis oil and concentrates for derivative products in Canada and Australia. It also provides cannabis contract processing services to licensed producers and growers; and tolling services to licensed cultivators in Canada. In addition, the company supplies purified cannabis concentrate raw materials and product formulations for ready-to-sell advanced cannabis products. Further, it engages in the real estate business. The company was founded in 2015 and is headquartered in Barrie, Canada.

Sante Veritas Therapeutics Inc. (CSE: SV) is striving to be one of Canada?s premier producer of pharma-grade, innovative, market-informed, cannabis products developed through state of the art genetics and grow environments, balancing market responsiveness with efficient production capabilities. PowerOne was finder and early investor in the company?s $7.7M financing in February 2017 and Co-Agent in the company?s $16M financing in December 2017. Sante Veritas has also announced a merger with Baker Technologies Inc., Briteside Holdings LLC, and Sea Hunter to form Tilt Holdings Inc., expanding into the United States and forming one of the most comprehensive industry platforms.

TILT Holdings Inc. (?TILT? or the ?Company?), which is a vertically-integrated technology and infrastructure platform delivering a comprehensive range of products and services across the cannabis industry.

True Health, also known as Sante Veritas Therapeutics, applied to the federal government and began the process to become a licensed producer for its marijuana for medical purposes regulations program.

Canopy Growth Corporation, formerly Tweed Marijuana Inc., is a cannabis company based in Smiths Falls, Ontario. Tweed was founded by Bruce Linton and Chuck Rifici in 2013, and renamed Canopy Growth Corporation in 2015 after a merger with Bedrocan Canada.

Xanthic, through its wholly-owned operating subsidiary, Xanthic Biopharma Limited, provides valuable intellectual property to cannabis industry participants, enabling its strategic partners to produce high quality, innovative, non-combustible cannabis, and cannabis-infused products which deliver consistent THC and/or CBD levels and improved bioavailability. Using a patent-pending proprietary process, Xanthic allows its strategic partners to deliver superior cannabinoid solubility, improved bioavailability, accurate micro-dosing and greater consistency versus competitive infused products. Through its investment in Xanthic Beverages, Xanthic has access to non-cannabis derived CBD-infused products that qualify for distribution outside of the cannabis dispensary network and into mainstream retail. www.xanthicbio.com